Years after surviving the T-virus outbreak in Racoon City, Leon S. Kennedy now works as a secret service agent for the U.S. President. After a cyber attack occurs at the White House, Leon finds himself teaming up with several other agents to defend the President from a zombie attack. He incidentally meets Claire Redfield who is investigating a possible zombie outbreak in Panamstan. Leon soon finds himself in the middle of a military conspiracy involving Panamstan and biological weapons. Can he trust his fellow agents? Will he and Claire be able to uncover the culprit behind the incidents in time before war breaks out?