Dr. Byrds & Mr. Hyde is the seventh studio album by the American rock band the Byrds and was released in March 1969 on Columbia Records. The album was produced by Bob Johnston and saw the band juxtaposing country rock material with psychedelic rock, giving the album a stylistic split-personality that was alluded to in its title. It was the first album to feature the new band line-up of Clarence White (guitar), Gene Parsons (drums), John York (bass), and founding member Roger McGuinn (guitar). Dr. Byrds & Mr. Hyde is unique within the band's discography for being the only album on which McGuinn sings the lead vocal on every track.

The album peaked at number 153 on the Billboard Top LPs album chart and reached number 15 on the UK Albums Chart. A preceding single, "Bad Night at the Whiskey" (b/w "Drug Store Truck Drivin' Man"), was released on January 7, 1969, but it failed to chart in the United States or in the United Kingdom. In addition, a non-album single featuring a cover of Bob Dylan's "Lay Lady Lay", which was recorded shortly after the release of Dr. Byrds & Mr. Hyde and also produced by Johnston, peaked at number 132 on the Billboard chart. Dr. Byrds & Mr. Hyde is the lowest charting album of the band's career in the United States, edging out the later Farther Along by one place.