Young bike-riding rebel Buzz visits his friend, old professor Doc, who's obsessed with ants. While looking at Doc's latest gadgets they discover some unusual ant and radioactive activity in the vicinity of their small desert town where minor atomic hazards sometimes occur. When townsfolk, including Buzz's stepparents, begin acting as if possessed, it's time for action. A mysterious friendly sax player offers Buzz (the player) a choice between gaining knowledge, strength or a girlfriend. Once the choice is made, Buzz is sent by Doc on various exploratory and combat missions which are presented as short playable side-scrolling shooting levels where Buzz must defeat various mutated and mind-controlled minions of AntMind. Between missions, he visits the local townsfolk who are becoming more and more unhinged and ant-like. AntMind often taunts Buzz and forces him to defend some of these characters in shooting gallery levels, where she sends flesh-eating ants to storm a possessed townsperson. Buzz also becomes enamored with a mysterious sexy brunette who talks to him through television. Buzz and Doc have only seven in-game days to find out what AntMind's ultimate goal is and defeat her before she takes over the town, them and then the world.