NoSleep began as a subreddit, or forum, on Reddit where people would exchange scary stories and frightening experiences. With the popularity of NoSleep, a member named Matt Hensen proposed the idea of creating a podcast where the top stories from the NoSleep subreddit would be narrated in an audiobook style.The idea was well received and a few months later a small group of members released the first episode of The NoSleep Podcast. During their first two seasons, David Cummings assumed the role of host and producer, working with volunteer Redditors to help narrate and produce content for the show.

The popularity of The NoSleep Podcast rapidly grew as the production quality became more professional. Regular voices on the show who provide narration for its stories include David Cummings, Jessica McEvoy, Peter Lewis, Nikolle Doolin, Nichole Goodnight, David Ault, Jeff Clement, Erika Sanderson, Addison Peacock, Mike DelGaudio, Atticus Jackson, Dan Zappulla, James Cleveland, Elie Hirschman, Kyle Akers, Alexis Bristowe, Jesse Cornett, Mick Wingert, and Erin Lillis. Despite horror arguably being a traditionally male-dominated genre, many of the narrators and authors of stories featured on the show, and also half of its 2 million regular monthly listeners are female.

Self-taught composer Brandon Boone, who joined The NoSleep Podcast in 2013, became responsible for the majority of the show’s music by Season 5. The NoSleep Podcast theme was written by David Cummings and has evolved with each season of the show. The show also works with a number of artists to create original illustrations for each episode. New episodes typically air every Sunday and contain five or six stories per episode, not including bonus releases. Every year the show also produces a new collection of the flash stories in their “Suddenly Shocking” series and a retro radio drama series, “Old Time Radio”. In 2015, the podcast was downloaded 600,000 times.

The NoSleep Podcast has also featured stories from authors who have gone on to publish their works, including the “Penpal” series from Dathan Auerbach, “99 Brief Scenes from the End of the World” by T.W. Grim, “What Happens When the Stars Go Out” by Jesse Clark, and “Psychosis" by Matt Dymerski. The NoSleep Podcast is also one of the few podcasts in its genre that pays its creative contributors.

Special guests that have appeared on the podcast include Mike Flanagan, Kate Siegel, Samantha Sloyan, Elijah Wood, and Kurtis Conner.